A 32-year-long surveillance study led by Sinai Health in Toronto has found that serious infections caused by group A streptococcus (iGAS) are rising in children, with the sharpest increase recorded in 2023. Strain types varied over time and were linked to differences in clinical severity and disease presentation. Most of the strains identified were types included in a 30-valent group A streptococcus vaccine that is currently in development.
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