Laying the groundwork for potential age-related macular degeneration therapies

Age-related macular degeneration (AMD) is a major cause of blindness, especially in older adults. A key feature of early AMD is the formation of drusen, clumps of debris made of lipids and proteins that collect between two layers at the back of the eye—the retinal pigment epithelium (RPE) and Bruch’s membrane (BrM).

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