Evidence lacking for new neurosteroid drugs in treating postnatal depression

Antidepressants are widely used as a drug based intervention to treat more severe cases of postnatal depression. While they are regularly prescribed, they can provide a limited response. The drugs modulate the gamma-aminobutyric acid (GABA) system—which has a key role in regulating brain activity—and have been proposed as an effective alternative to antidepressants.

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