Male, female knee cartilage disparities may explain differences in rates of degeneration

Researchers have long known there are sex disparities when it comes to the prevalence and severity of knee osteoarthritis, a disease that causes cartilage degeneration. Now, investigations underway at UT Southwestern Medical Center point to biological differences in the knee cartilage of male and female animals that could explain substantial variances in rates of osteoarthritis between the sexes and may eventually lead to tailored treatments that take these into account.