Cart is empty Anaplastic large cell lymphoma, a form of non-Hodgkin lymphoma, is the most common aggressive lymphoma in children. Chemotherapy and radiation fail to cure about 30% of cases. When tumors are driven by the oncogene ALK—which is the case for the majority of children—kinase inhibitor drugs like crizotinib are very effective in blocking tumor growth. They also lack the serious side effects of chemotherapy.
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