New test improves quality control of allergy therapeutics

An interdisciplinary research team from the Allergology and Veterinary Medicine Divisions at the Paul-Ehrlich-Institut (PEI) has developed a novel laboratory test that enables the determination of adjuvanted allergoids in finished medicinal products. Content analyses of finished medicinal products were not possible in the past due to the complex structure of this medicinal product group, which contains both adjuvants and allergoids (chemically modified allergens) and therefore had to be performed on an intermediary production step.

Disadvantaged backgrounds can leave a lifelong accelerated aging marker in children

Economic disadvantage leaves a biological imprint on children which could last throughout their lifetime, reducing their quality and length of life. These are the findings of a study of more than 1,000 European children led by researchers at Imperial College London. The research finds evidence that the impacts of socioeconomic status can be seen in the blood cells of children, with those from less privileged backgrounds having shorter telomeres—an established biomarker for aging.

Blood test shows 95% accuracy for Alzheimer’s disease diagnosis in outpatient memory clinics

Alzheimer’s disease, marked by memory loss, trouble concentrating and thinking, and changes in personality and behavior, devastates patients, their families and loved ones. With new treatments available for people with early signs of Alzheimer’s disease, there is a growing need for accessible and cost-effective tests to diagnose Alzheimer’s disease sooner.

Silent struggles of post-9/11 veterans linked to rising suicides

Post-9/11 veterans often face visible challenges like finding gainful employment or recovering from physical injuries, but some of their struggles are invisible. Veterans may carry a sense of isolation and the painful belief that their presence is a burden to those around them. When these thoughts persist over time, they could contribute to an increased risk of suicide, according to a new study by researchers at the Clearinghouse for Military Family Readiness at Penn State (Clearinghouse).