A common enzyme takes on a surprising role in preventing cancer

Researchers at Duke University Medical Center and Wake Forest University School of Medicine have identified ALDH4A1, a mitochondrial proline-metabolizing enzyme, as a third structural component of the mitochondrial pyruvate carrier (MPC) complex. Forming a trimeric assembly with MPC1 and MPC2, ALDH4A1 maintains MPC integrity and facilitates pyruvate import into mitochondria.

Study explores mentions of substance use, mental health in pop music since 2013

New research presented May 17 at the American Psychiatric Association’s Annual Meeting examines trends in the way popular music reflects national trends in substance use and mental health. Because of their cultural impact, pop songs shape how substance use is discussed and can potentially serve as an important public health tool to help reduce stigma and promote healthy habits.