Rediscovering denosumab: From osteoporosis medication to a possible treatment for breast cancer

Science and society collaboration is essential for scientific progress, especially in the health and biomedical fields where basic researchers, clinicians and patients are involved, as shown by the initial results of D-BIOMARK. This clinical trial against breast cancer has analyzed the potential anti-tumor role of denosumab, a drug already in use in the prevention of metastasis-related osteoporosis and bone lesions.

Midlife intakes of high-quality carbohydrates and dietary fiber linked to better health in older women

Intakes of dietary fiber, high-quality and total carbohydrates in midlife were favorably linked to healthy aging and other positive health outcomes in older women, according to a new study by researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University and Harvard T.H. Chan School of Public Health.

Fruit fly study links Alzheimer’s proteins to widespread organ changes and sensory decline

While Alzheimer’s disease is mostly considered a disorder of the brain, emerging evidence suggests that the condition also affects other organs of the body. Working with the laboratory fruit fly, researchers at Baylor College of Medicine, the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (Duncan NRI) and collaborating institutions provide a new understanding of how Alzheimer’s disease affects different tissues across the entire body.