A Cornell University project to save babies born with serious heart defects has lost key funding just days after it was approved.
Exploring sex differences in neurological conditions
Conditions such as Tourette syndrome (TS), schizophrenia, and attention-deficit/hyperactivity disorder (ADHD) have sex differences with unknown mechanisms. These sex-specific mechanisms may inform the development of more effective treatments.
ChatGPT helps pinpoint precise locations of seizures in the brain, aiding neurosurgeons
Epilepsy, one of the most common neurological disorders characterized by recurrent seizures, affects over 70 million people worldwide. In the United States, about 3.4 million people live with this challenging condition. Around one-third of the epilepsy cases cannot be controlled by medications. For those patients, surgical resection of the epileptogenic zone (EZ), an area whose removal can lead to seizure freedom—a period of time when a person with epilepsy experiences no seizures—can be an effective option to reduce or eliminate seizures.
Bindi Irwin was rushed to hospital for appendix surgery. But what is appendicitis?
Bindi Irwin has reportedly been rushed to hospital in the United States to undergo emergency surgery for a ruptured appendix.
Do wellness patches work? How to tell the good from the bad
From sleep aids and stress relief to vitamins and energy boosts, wellness patches are surging in popularity. These stick-on supplements promise to deliver nutrients and plant-based compounds directly through your skin and into your bloodstream—no pills, no needles, no fuss.
Molecular approach prolongs ketamine’s antidepressant effects in mice by weeks
Researchers at Vanderbilt University identified a molecular approach to extend the antidepressant effects of ketamine in mice by applying BCI, a compound that inhibits DUSP6 to sustain ERK pathway activation. Findings suggest that BCI modulates the duration of ketamine’s synaptic and behavioral effects, potentially reducing the need for repeated dosing and associated side effects.
‘I don’t even recognize myself anymore’: The reality of eating disorders in sport
The UK is facing what charities are calling an eating disorder epidemic, with an estimated 1.25 million people affected. These conditions have the highest mortality rate of any mental health illness, making early intervention and education urgent.
Cell-by-cell roadmap reveals key transcription-factor ‘switches’ in neuroblastoma
High-risk neuroblastoma kills roughly half of affected children because the tumor can switch cell identity and evade therapy. By combining single-cell multi-omics with spatial transcriptomics, researchers at Karolinska Institutet have constructed a cell-by-cell roadmap of these state transitions. The paper is published in the journal Developmental Cell.
Endometriosis: Daily pill to manage symptoms will soon be available on the NHS—here’s how linzagolix works
A daily pill to treat endometriosis has just been recommended by the National Institute for Health and Care Excellence (Nice). Once available on the NHS, linzagolix will provide a new treatment option for those who have been unable to manage the condition using other standard treatments.
GLP-1 receptor agonists show anti-cancer benefits beyond weight loss
New research being presented at the European Congress on Obesity (ECO25) in Malaga, Spain (11–14 May) and published in the journal eClinicalMedicine finds that first-generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss.