All posts by : Felistas

Cleveland Clinic researchers are working to improve the way we use evolutionary modeling to understand drug resistance. The study, published in Science Advances, uses a new type of evolutionary model called a “fitness seascape” to incorporate a patient’s dosage schedule into models that predict whether an infection will develop antibiotic resistance, and has found that inconsistent timing and missing early doses can lead to treatment failure.

New research from the University of Minnesota Medical School suggests that different genetic forms of autism may lead to similar patterns in brain activity and behavior. The findings were recently published in Nature Neuroscience.

It is known that vasculopathy plays a pivotal role in the pathogenesis of systemic sclerosis (SSc). Vasoactive vasodilating drugs (VVD) are an option. The most recent treatment recommendations from EULAR—The European Alliance of Associations for Rheumatology—note that advances in vasculopathy management for patients with SSc emphasize a treatment continuum for the use of various VVD, but also stress the need for trials to look for potential synergistic combinations as well as high-quality real-world data to build the evidence. New data shared at the 2025 EULAR congress in Barcelona may take a step in that direction.

Be it peanuts or other triggers, many families live with the day-to-day risk that their child might experience a sudden and scary allergic reaction. Pediatric emergency department visits in the United States to treat acute allergic reactions more than tripled from 2008 to 2016.

Immunotherapy has revolutionized cancer treatment by mobilizing the immune system to attack tumor cells. Major advances, such as immune checkpoint inhibitors (notably against the PD-1 protein), have produced impressive results against certain types of cancer, including melanoma and kidney cancer.

Axial spondyloarthritis (axSpA) is a chronic inflammatory rheumatic musculoskeletal disease that predominantly affects the axial skeleton. axSpA is an umbrella term that comprises the whole spectrum of patients with and without radiographic sacroiliitis, and joint ASAS/EULAR recommendations were published in 2022.

EULAR—The European Alliance of Associations for Rheumatology—believes that nurses are an important part of the health care team, especially for providing evidence-based care and endorsing shared decision-making in consultation with the patient. This is also important considering the shortage of rheumatologists in Europe, which means delegation is necessary.

Osteoarthritis is a leading cause of chronic pain, often affecting physical function, daily activities, and quality of life. EULAR—The European Alliance of Associations for Rheumatology—has developed recommendations and clinical practice guidelines for the management of osteoarthritis in the hand, hip, and knee.

Regular physical activity is increasingly promoted for people with rheumatic and musculoskeletal diseases (RMD) as well as the general population. EULAR—The European Alliance of Associations for Rheumatology—has published recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. There are also points to consider on helping people participate in healthy and sustainable paid work.

About 525,000 more deaths occurred among US adults in 2023 than would be expected had pre-2010 mortality trends continued. More than 90% of these deaths occurred among individuals without a bachelor’s degree and were largely caused by cardiovascular diseases, underscoring how educational attainment can influence individuals’ health opportunities and outcomes.