As prevention strategy for sexually transmitted infections rolls out, experts highlight both promise and knowledge gaps

As health care services begin offering doxycycline to prevent bacterial sexually transmitted infections (STIs), real-world evidence demonstrates that the postexposure strategy, called doxy PEP, is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.

Exploring IL-8⁺ neutrophils and their role in severe alcohol-associated hepatitis

Alcohol-associated hepatitis (AH) is a critical global health issue characterized by acute liver inflammation and an elevated risk of mortality in its severe form (sAH). While the condition has been studied extensively, effective treatments remain scarce, with liver transplantation often being the only viable option for patients with advanced disease.

Genetic testing could improve treatment for patients with the virulent multidrug-resistant fungus Candida auris

A new study shows that genetic testing could be used to determine which drugs will—and won’t—work for patients with Candida auris (C. auris), a multidrug-resistant yeast that causes life-threatening disease. These findings could improve treatment for C. auris infections by enabling patients to start taking effective antifungal agents sooner.