Obese mice whose fat cells were genetically altered to produce an increased amount of the glucose-dependent insulinotropic polypeptide receptor (GIPR) lost more than a third of their body weight through a mechanism that burns energy, UT Southwestern Medical Center researchers report in a new study.
Genetic discovery offers hope for personalized epilepsy treatments
Recent research led by UTHealth Houston scientists has uncovered two genes associated with variants linked to epilepsy, which showed specific traits that make them promising diagnostic biomarkers.
Prioritizing resources for GPs in deprived areas found to be essential for care
General practitioners (GPs) in deprived areas should be prioritized for resource, in order to allow them to provide effective care to some of the most unwell and vulnerable patients in society.
Discovery of immune-boosting fibroblasts offers hope for cancer patients
Southampton scientists working to improve survival for cancer patients have identified a key characteristic of the disease that could make treatment more effective.
Digital heart twin offers potential new tool for treating dangerous heart rhythms
Using computers to make a digital replica of the heart—a digital heart twin—can successfully identify problem areas deep in the heart muscle of people with a serious heart rhythm disorder, a new study finds. The research lays the groundwork for a new way of treating a life-threatening condition often caused by prior heart attacks or genetic heart disorders.
Risk of domestic abuse increases over time for those exposed to childhood maltreatment, twins study suggests
The risk of experiencing intimate partner violence may accumulate over time among people who experienced childhood maltreatment when they were younger, finds a new study led by UCL researchers.
Bile acids’ surprising role in food allergy treatment revealed
Metabolites—small molecules within cells, biofluids, tissues or organisms—play an integral role in various diseases, and studying the many metabolites (metabolomics) can teach us how the body works in ways that help researchers develop new treatments, especially for food allergens.
Mixed signals: Mouse moms study explores how brain merges smell and sound cues
Imagine you’re at a dinner party, but you can’t smell the food cooking or hear the dinner bell. Sounds like a dream, right? What if it wasn’t? “When we experience the world and interact with people, we use all our senses,” Cold Spring Harbor Laboratory Professor Stephen Shea says. “That’s true for animals and humans.”
Study reveals rising interest in permanent contraception after Roe v. Wade reversal
A study from George Washington University found a significant increase in the number of U.S. young adults seeking permanent contraception, specifically tubal sterilization and vasectomy, following the Supreme Court’s June 2022 decision which overturned Roe v. Wade.
Machine learning and climate data offer new insights into dengue forecasting
Dengue is a mosquito-borne disease which infects about 390 million people globally each year. Case numbers have grown steadily in recent years, with the most severe outbreaks occurring in tropical regions of South America. To better predict how the disease spreads, it will be vital for researchers to fully understand how dengue case numbers are linked to different aspects of tropical climates.