A novel immuno-PET/CT imaging technique has identified and validated a potent biomarker for nasopharyngeal cancer (NPC). The biomarker, CD70, is highly and constantly expressed in NPCs, and CD70-targeted immuno-PET/CT has proven effective in accurately detecting primary and metastatic NPC lesions.
Muscle ‘control center’ discovery could help elderly with better muscle healing
When a house is hit by a hurricane, you must first remove the damaged parts before reconstruction can begin. The same applies to our muscles after injuries—and now researchers from Aarhus University and Steno Diabetes Center Aarhus have discovered who functions as the coordinator of this repair process.
Preventing stalling to improve CAR-T cells’ efficacy against tumors
Chimeric antigen receptor (CAR)-T cells are a promising cancer therapy that are made from the patient’s own T cells, which are reprogrammed to fight their cancer. One of the limitations of CAR-T cell therapy is the ability of these cells to survive long enough to target the entire tumor.
Two biomarkers that may predict diabetic foot ulcer healing outcomes identified
Diabetic foot ulcers (DFUs) are a major clinical challenge, with high rates of morbidity, disability, amputations and mortality. Despite extensive research, effective predictive biomarkers for DFUs healing remain elusive.
First data from the EULAR RheumaFacts project
Rheumatic and musculoskeletal diseases (RMD) are the leading causes of disability worldwide, resulting in significant health care and social support costs. One of the reasons for this increasing burden seems to be the variability in the number and nature of allocated resources across Europe, as well as organizational aspects of health systems that result in disparities and health inequities across countries.
Guidance needed for RMD patients seeking help online
Rheumatic musculoskeletal diseases (RMD) have an important impact on quality of life, and represent an economic burden to society. EULAR—The European Alliance of Associations for Rheumatology—has emphasized the role of patient empowerment through education.
Patient organizations: Supporting RMD patients with education
When receiving a diagnosis of a rheumatic musculoskeletal disease (RMD), people need a lot of information. Some need it all at once, while others may prefer to receive it in smaller portions or like to spread it out. This can mean that rheumatologists and other health care professionals do not always know how best to support patient education.
Clinically deployed AI guidance may prevent C. difficile spread
AI guidance for clinicians aimed at reducing the spread of Clostridioides difficile—a bacteria that can be deadly for sick patients—was deployed for the first time in a hospital setting, according to a University of Michigan-led study published in JAMA Network Open.
Experimental model for myelodysplastic syndromes uncovers genetic alterations to improve characterization
Myelodysplastic syndromes (MDS) are a group of disorders that typically arise in adulthood, especially after the age of 70, and their five-year survival rate is around 30%. MDS are characterized by defective maturation of blood cells in the bone marrow, leading to a range of health problems such as fatigue and recurrent infections. Without appropriate treatment, they may progress to acute myeloid leukemia, a much more severe disease.
AI tool analyzes blood DNA fragments for faster, affordable cancer monitoring
Scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new artificial intelligence (AI)-based method called “Fragle” that makes tracking cancer easier and faster using blood tests.