A blood-based test has acceptable accuracy for colorectal cancer detection but not for advanced precancerous lesions in an average-risk colorectal cancer screening population, according to a study published online June 2 in the Journal of the American Medical Association.
New antibody shot could help protect babies from RSV
A newly approved shot could soon help protect babies from respiratory syncytial virus (RSV), the top cause of hospitalization in U.S. infants.
Key mechanism that leads to high blood pressure uncovered
When someone has high blood pressure, or hypertension, it results in changes to the walls of their blood vessels. This process is known as arterial or vascular remodeling, which is driven by smooth muscle cells in the blood vessel wall. Researchers at Michigan Medicine have uncovered a key mechanism that regulates blood pressure and vascular remodeling—increasing downstream risk of heart attack and stroke—in people with a genetic variant linked to high blood pressure, a study in both animals and human samples suggests.
Hemophilia B gene therapy demonstrates long-term success
A gene transfer approach to treating the bleeding disorder hemophilia B remains safe and effective long-term, as scientists from St. Jude Children’s Research Hospital and University College London today report thirteen years of follow-up data. Hemophilia B is a rare genetic disorder caused by insufficient levels of a circulating protein called factor IX, which promotes blood clotting.
Structural brain changes identified up to 15 years before Alzheimer’s symptoms in people with Down syndrome
A study led by the Sant Pau Research Institute (IR Sant Pau) has succeeded in describing, for the first time in detail, the structural evolution of the medial temporal lobe (MTL) regions across the clinical stages of Alzheimer’s disease in people with Down syndrome. The results, published in the journal Brain, reveal that volume and cortical thickness loss in these regions can begin 13 to 15 years before the onset of symptoms, marking a significant advance in early diagnosis and the design of preventive clinical trials.
Blood conservation technique does not reduce need for transfusions, international study finds
An international study published today in the New England Journal of Medicine sheds light on acute normovolemic hemodilution, also known as ANH, a blood conservation technique.
Sleep apnea found to be more prevalent in young female athletes than expected
According to a new study, presented at the American College of Cardiology (ACC) Care of the Athletic Heart 2025 conference, sleep apnea may be more prevalent in younger female athletes than previously believed, especially among female athletes with higher levels of training. While obstructive sleep apnea has been observed in younger male athletes, the prevalence in female athletes and the association with cardiovascular risk is largely unknown.
Study shows sharp contrasts in complementary and alternative medicine use across countries
Contrary to expectations, the COVID pandemic did not cause a spike in the overall use of complementary and alternative medicine (CAM) in Europe: the growth was modest, from 27% in 2014 to 28% in 2023. These University of Helsinki findings are reported in an article published in the Journal of Public Health.
Reviving indigenous languages linked to improved public health outcomes, new research shows
In British Columbia, First Nations youth who speak their ancestral language are less likely to die by suicide. In Australia’s Northern Territory, community-led language initiatives are linked to better mental health outcomes.
Novel assay promises more efficient screening for carriers of fragile X syndrome
Researchers have developed an innovative new nanopore sequencing assay to identify carriers of fragile X syndrome (FXS), the leading cause of monogenic autism spectrum disorder and inherited intellectual disabilities. The study, published in The Journal of Molecular Diagnostics, addresses the urgent need for a screening tool to identify carriers of FXS in a more comprehensive, faster, efficient, and cost-effective way compared to current methods, for better informed genetic counseling.