A growing number of firearm suicides in the United States occur outside the home, most commonly in motor vehicles, according to a study published online in JAMA Network Open.
Genetic changes control metastasis formation in colorectal cancer
Colorectal cancer is one of the most common types of tumor and is responsible for around 10% of cancer-related deaths worldwide. The tumor is particularly dangerous when it forms metastases—i.e. secondary tumors—in other organs. This occurs primarily in the liver and lungs, and more rarely in the brain.
Could the same technology that enables targeted immunotherapy for cancer be used to tackle Alzheimer’s?
Inspired by advances in cancer therapy, a team at the Buck Institute has engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau tangles and various forms of toxic amyloid plaques, both of which are implicated in Alzheimer’s disease pathology.
A combination of exercise and omega-3 can reduce the severity of tooth root infections
A study published in the journal Scientific Reports indicates that physical exercise combined with omega-3 supplementation considerably improves the immune response and reduces the severity of chronic apical periodontitis.
Out-of-body experiences linked to trauma response and stress coping mechanisms
Out-of-body experiences—where people feel like spirits disconnected from their physical form—may be a coping mechanism triggered by trauma or other overwhelming stress, new University of Virginia School of Medicine research suggests.
New, non-opioid molecule acts like a long-lasting anesthetic, relieving chronic pain for three weeks
A new molecule developed by University at Buffalo researchers acts like a local, long-lasting anesthetic, providing robust pain relief for up to three weeks, according to the results of preclinical studies reported recently in the journal Pain.
Lab-grown mini-intestines map how Shigella bacteria invade human gut tissue
Thanks to lab-grown miniature intestines, researchers at Uppsala University have successfully mapped how aggressive Shigella bacteria infect the human gut. The study opens the door to using cultured human mini-organs to investigate a wide range of other serious infections.
Depression linked to a less diverse oral microbiome
A rich and varied mix of microbes in the mouth, particularly bacteria, is not only important for our oral health, but may hold clues for other conditions.
How choroid plexus apocrine secretion shapes fetal brain development
The human brain, like the brain of other mammals, is known to start developing before birth, via a coordinated sequence of molecular and cellular processes. Neuroscience studies have found that the choroid plexus (ChP), a specialized brain structure that regulates the production of a liquid that nourishes the brain and spinal cord, plays a key role in the brain’s early development.
Too busy to focus on your happiness? Try daily micro-acts of joy
Researchers, led by UC San Francisco, tested the effectiveness of a weeklong, web-based well-being intervention, known as the Big Joy Project. This consisted of daily micro-acts, which included asking someone to share a fun, inspiring, or proud moment, making a gratitude list, and performing a kind act to brighten someone’s day.