In the 1980s, when Stella Kourembanas, MD, began her career in neonatology, she cared for newborns with pulmonary hypertension, a disease that results in abnormally high blood pressure in the lung arteries and can lead to heart failure. Since then, treatments like inhaled nitric oxide, new vasodilators, new modalities of mechanical ventilation, and extracorporeal membrane oxygenation (ECMO) have reduced mortality from about 85% to 10%. But pulmonary hypertension still persists.
Wi-Fi-based technology developed to detect depression in older adults
A new study published in JMIR Aging developed and tested a new AI model called HOPE which uses Wi-Fi-based motion sensor data to detect depression in older adults without relying on intrusive wearable devices. The research highlights a novel machine learning model that accurately detected depression among participants.
Study finds new potential for prostate cancer immunotherapy
A new study by University of Arizona Health Sciences researchers found that an immunotherapy previously shown to be ineffective against prostate cancer may have therapeutic potential when combined with a synergistic treatment approach. The paper was published in the journal Cancer Immunology Research.
Diesel exhaust exposure leads to disarray in liver function in mice; could also indicate health issues for humans
UCLA Health researchers have discovered significant changes in liver function following exposure to diesel exhaust (DE) in a controlled study involving mice. The study identified disrupted activity in 658 genes and 118 metabolites. These changes led to a higher production of triglycerides, fatty acids, and sugars, largely due to problems with mitochondria, an organelle in the cell responsible for energy production.
Consumer devices can be used to assess brain health, study shows
Technology is changing how physicians think about assessing patients, and in turn, how patients expect to be able to measure their own health. Apps designed for smartphones and wearable devices can provide unique insights into users’ brain health.
Exploring clusters of metabolic dysfunction-associated steatotic liver disease for precision medicine
Globally, more than 30% of the adult population has metabolic dysfunction-associated steatotic liver disease (MASLD). People with MASLD and more so with metabolic dysfunction-associated steatohepatitis (MASH) and MASLD-associated hepatic fibrosis can progress to cirrhosis and hepatocellular carcinoma and are at increased risk of developing type 2 diabetes, cardiovascular disease, chronic kidney disease, and extrahepatic cancers.
Barriers in cancer screening for people with intellectual disabilities highlight need for tailored support
People with intellectual disabilities (ID) are significantly less likely to participate in population-based cancer screening than the general population, according to researchers from Radboudumc and the academic collaborative Intellectual Disability and Health.
Anxiety vs. apathy: How the two emotional states lead to fundamentally different decision-making patterns
Making decisions in uncertain situations is part of daily life. New research from the University of Minnesota Medical School has uncovered that anxiety and apathy—two common but distinct emotional states—lead to fundamentally different patterns in how people learn and make decisions.
Foundation AI model predicts postoperative risks from clinical notes
Millions of Americans undergo surgery each year. After surgery, preventing complications like pneumonia, blood clots and infections can be the difference between a successful recovery and a prolonged, painful hospital stay—or worse. More than 10% of surgical patients experience such complications, which can lead to longer stays in the intensive care unit (ICU), higher mortality rates and increased health care costs. Early identification of at-risk patients is crucial, but predicting these risks accurately remains a challenge.
Youth with concussion may benefit from monitoring sleep and limiting daytime naps, study finds
Researchers at Nationwide Children’s Hospital have found that when it comes to concussion recovery, sleep matters. In a study published in the British Journal of Sports Medicine, researchers found that limiting daytime sleep and getting approximately seven hours of sleep each night in the first week after a concussion may speed up recovery.
