A new article in the journal Nucleic Acid Therapeutics addresses the recognition by the U.S. Food and Drug Administration that immunogenicity assays may be necessary to measure immune responses to different components of oligonucleotide therapeutic (ONT) drugs, especially when the therapeutic includes carriers or conjugates.
Two video games created to improve hand and wrist rehabilitation
Universidad Carlos III de Madrid (UC3M), in collaboration with Escuela PolitĂ©cnica del Ecuador and the ASEPEYO hospitals in Barcelona and Madrid, has developed a system of exercise video games (or exergames) that promotes the rehabilitation of people with mobility problems in their hands and wrists. The system also provides data to therapists so that they can analyze their patients’ progress during the recovery stage.
One in five people who use alcohol and other drugs have symptoms of ADHD
A new research report shows that 1 in 5 people using drugs and alcohol have symptoms of ADHD and that this rate increases to over one-third among people using benzodiazepines. The report—launched at a seminar this morning in Dublin’s Wynn’s Hotel—also shows that the highest rates of ADHD overall were found among women using these drugs.
Engineered strain reveals key mechanism behind bacterial cancer therapy
A research team has elucidated the mechanism behind bacterial cancer therapy using a genetically engineered bacterial strain. Their findings were published in Cell.
How to trick the body’s metabolism: Mouse study reveals new path for weight-loss and diabetes treatments
Many people who have tried to lose weight by cutting calories are familiar with this frustrating reality: At some point, the body stops shedding pounds. It senses the reduced calorie intake and responds by slowing down metabolism, causing it to burn fewer calories than before the diet.
A shift in diabetes testing after pregnancy could improve women’s health
Caring for a baby is a full-time job, often causing new mothers to overlook their own health needs. This situation is exemplified by the low compliance with postpartum glucose screening among women who had gestational diabetes—a condition that significantly increases their risk of developing type 2 diabetes later in life.
FDA makes access to clozapine easier for patients with schizophrenia
The U.S. Food and Drug Administration has removed one hurdle faced by patients with schizophrenia when filling prescriptions for the antipsychotic medication clozapine.
Vaccination rates are declining and might get worse as states relax rules
More states are loosening vaccine mandates, scaling back vaccine promotion efforts and taking other steps likely to lower vaccination rates—even as a major measles outbreak spreads in Texas.
Ultra-processed foods are everywhere: How bad are they?
Scan any aisle in a convenience or grocery store, and those brightly packaged, bold-lettered, sweet-and-salty options are likely to be ultra-processed.
How to treat spring allergies: A graduated approach
Spring brings warmer weather, but for allergy sufferers, it also means sneezing, wheezing and itchy eyes. Instead of enjoying the season, you may be battling congestion and brain fog. So, what can you do to manage your spring allergy symptoms?