An aromatic lexicon: Comprehensive fragrance database offers insights into human perception of odors

People all over the world largely agree on what the color blue looks like or what the shape of a ball feels like. But when it comes to describing odors, opinions often differ. This is because, unlike the processing of wavelengths of light in the brain, which makes it possible to determine colors relatively clearly, it is still not easy to deduce the smell of substances in our environment from their chemical composition.

Key form of tau protein identified for understanding and treating Alzheimer’s disease

A research team at the University of Cologne has made a significant breakthrough in understanding the role of the tau protein in Alzheimer’s disease. Using human induced pluripotent stem cells (iPSCs), the international team has been able to show that a specific form of the tau protein, known as the 1N4R isoform, is responsible for mediating the toxic effects of protein clumps in human brain cells.