Llama-derived antibodies target coronaviruses’ conserved spike region, offering broad protection

Scientists have discovered a unique class of small antibodies that are strongly protective against a wide range of SARS coronaviruses, including SARS-CoV-1 and numerous early and recent SARS-CoV-2 variants. The unique antibodies target an essential highly conserved site at the base of the virus’s spike protein, effectively clamping it shut and preventing the virus from infecting cells.

Monitoring bone healing without X-ray radiation: A new approach lights the way

A medical research team at Saarland University, led by Professor Bergita Ganse, has discovered a new approach to monitoring bone fracture healing by measuring blood supply to the tissue at the fracture site and the level of oxygen in the blood. Bone regeneration can be monitored quickly and easily using near-infrared light rather than harmful shorter wavelength radiation.

New immune targets identified in glioblastoma: CD44 and TNFSF14 may help guide future therapies

Glioblastoma (GBM) is the most aggressive and lethal form of brain cancer, with a median survival of only 15 months despite intensive treatment. Current therapies—including surgery, radiation, and chemotherapy—offer limited long-term benefit, and immune-based treatments have so far shown minimal success. The complexity of the tumor’s microenvironment and its ability to suppress immune responses contribute to the poor prognosis.