Cart is empty Walking is a fundamental activity for maintaining health. While numerous studies have assessed how much people with chronic obstructive pulmonary disease (COPD) walk, few have explored how they walk, especially in unsupervised, real-life settings.
Addition of regional nodal irradiation does not decrease rates of invasive breast cancer recurrence, study finds
Recent results from the NRG-NSABP B-51/RTOG 1304 clinical study showed that the addition of regional nodal irradiation (RNI) does not decrease the rates of invasive breast cancer recurrence in patients whose positive axillary nodes at presentation convert to negative following neoadjuvant chemotherapy. These results were recently published in the New England Journal of Medicine.
Combination therapy shows superior efficacy in reducing albumin in chronic kidney disease and type 2 diabetes patients
New data from the CONFIDENCE trial demonstrates that combination therapy with finerenone and empagliflozin leads to significantly greater reductions in albuminuria than either agent alone in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D). The breakthrough study was presented today at the 62nd ERA Congress and published in the New England Journal of Medicine.
Brain mechanisms that distinguish imagination from reality discovered
Areas of the brain that help a person differentiate between what is real and what is imaginary have been uncovered in a new study led by UCL researchers.
Cancer treatments should be licensed for all ages, oncologists say
Recent advances have resulted in highly effective “tissue-agnostic” drugs that treat cancers based on their molecular markers rather than their tissue of origin, but very few of these drugs are approved for use in children. In an opinion paper published in the journal Trends in Cancer, oncologists call for “ag(e)nostic” cancer treatments: drugs that are both tissue agnostic and approved for cancer patients of all ages.
Biweekly dose of TAS-102 reduces toxicity and remains effective for treatment of colorectal cancer, says study
Patients with metastatic colorectal cancer who were treated with a biweekly dose of trifluridine-tipiracil (TAS-102) saw similar treatment effectiveness and reduced toxicity compared with treatment using standard dosing schedules, according to a recent study in The Oncologist that was co-authored by a Fox Chase Cancer Center physician.
Informal caregivers of heart patients need more support—our study shows where to begin
If you’ve ever cared for someone through illness, you know that healing doesn’t just happen in hospitals or clinics. It happens at home—around dinner tables, during medication routines, and in countless quiet moments where someone chooses to stay, care and keep going.
How a synthetic lipoprotein targets tumor metabolism to trigger cancer cell death
Northwestern Medicine scientists have developed a promising approach to killing treatment-resistant cancer cells by exploiting their hidden metabolic vulnerabilities, according to a study published in the Proceedings of the National Academy of Sciences.
Study shows how obesity can affect care provision
A new study has found that older adults living with obesity can feel judged or dismissed by care providers due to their weight, leading to a reluctance to seek help.
Global study finds no link between mRNA COVID-19 vaccines and Guillain-Barré syndrome risk
A new multinational study analyzing data from over 230 million people across 20 global sites highlights the relationship between SARS-CoV-2 infection, certain COVID-19 vaccines, and Guillain-Barré syndrome (GBS). This research reinforces the importance of continuous vaccine safety monitoring and highlights key differences in risk associated with different vaccine types.