Peristaltic pump flow: A potential trigger for amyloid protein aggregation

The factor that tips you over the edge from being at risk for a disease to actually developing the disease is not always clear. Now, researchers from Japan report one factor that triggers problematic proteins to start behaving badly. In a study published recently in npj Biosensing, researchers from Osaka University have revealed that high liquid flow rates could cause aggregation-prone proteins to start sticking together.

New laparoscopic imaging technique accurately maps biological tissue for minimally invasive surgery

Laparoscopy, a minimally invasive surgical technique, has become the standard of care for many procedures such as prostatectomies and appendectomies due to its benefits, including faster recovery times, reduced scarring, and lower medical costs. However, the technique faces challenges in visualization, particularly when it comes to identifying critical anatomical structures, assessing tissue perfusion, and distinguishing cancerous tissue.

Chagas disease study in Paraguay supports use of rapid tests to improve access to diagnosis

Rapid tests could be used to diagnose Chagas disease in resource-limited areas, according to a study led by the Barcelona Institute for Global Health (ISGlobal). The results of this research, published in PLOS Neglected Tropical Diseases, show that the prevalence of Chagas in an indigenous community in Paraguay is six times higher than in the country’s capital.

Analytical framework reveals key insights into time persistence in human brain networks

A new international and multidisciplinary study has unveiled a novel framework for understanding the concept of time persistence in the human brain, shedding light on its essential role in brain functioning and cognition. This research, which explores how long the brain’s functional networks remain in a particular state before transitioning to another, opens new doors to our understanding of human cognition and behavior.

Stroke researchers discuss finding silver linings in three recent neuroprotection studies

The Calgary Stroke Program, a joint University of Calgary and Alberta Health Services initiative at Foothills Medical Centre, has been involved with three papers published this week in The Lancet and Lancet Neurology—the ESCAPE-NEXT trial, the FRONTIER trial, and an individual patient-level meta-analysis across three trials. The studies, in collaboration with NoNO Inc., are focused on neuroprotection and ischemic stroke. While the primary trials were inconclusive, the meta-analysis reveals that the data provide important clues for future research into stroke treatment.