All posts by : Felistas

NDORMS researchers have identified a primary source of inflammatory IL-17 driving spondyloarthritis, paving the way for the development of targeted therapies to treat the condition.

New 100-week data from the ongoing Phase I/II study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN). Findings presented at the 62nd ERA Congress demonstrate sustained proteinuria remission, stable kidney function, and a reassuring safety profile.

GLP-1 (glucagon-like peptide-1) therapies can be powerful tools in managing obesity, with patients taking these medications seeing weight reductions of 5%–18% in clinical trials, along with increased metabolism and benefits to their overall heart health. However, GLP-1s can come with challenges, including gastrointestinal side effects, risk of micronutrient deficiencies, muscle and bone loss, poor long-term follow-through with weight regain if stopped, and high costs.

Jail time has a huge effect on both an individual’s and a community’s long-term health, even after their release, a new study says.

Using an algorithm they call the Krakencoder, researchers at Weill Cornell Medicine are a step closer to unraveling how the brain’s wiring supports the way we think and act. The study, published June 5 in Nature Methods, used imaging data from the Human Connectome Project to align neural activity with its underlying circuitry.

A major international study presented at the 62nd ERA Congress reveals that the long-accepted survival advantage of deceased-donor kidney transplantation does not extend equally to every patient and every donor organ.

Navajo Nation leaders took turns talking with the U.S. government’s top health official as they hiked along a sandstone ridge overlooking their rural, high-desert town before the morning sun grew too hot.

Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors. Metastatic melanoma, as the disease is formally named, kills nearly 10,000 Americans annually.

A study published in the New England Journal of Medicine reveals that the largest diphtheria epidemic in Western Europe for 70 years, which broke out in 2022 among migrants and in 2023 spread to other vulnerable populations in several European countries, is the result of contaminations occurring during migratory travel or in destination European countries, and not in the countries of origin.

A study of almost 1,000 pregnant women in Zimbabwe found that a daily dose of a commonly used, safe and inexpensive antibiotic may have led to fewer babies being born early. Among women living with HIV, those who received the antibiotic had larger babies who were less likely to be preterm.