QIMR Berghofer-led research in collaboration with Australian oncology company Kazia Therapeutics has found that combining the drug candidate paxalisib with immunotherapy triggered a molecular epigenetic process that prevented the spread of cancer cells and overcame treatment resistance in preclinical models of triple negative breast cancer.
Arizona officials confirm measles outbreak in Navajo County
Health officials in Arizona say there are four linked measles cases in Navajo County, marking the state’s first outbreak this year.
Social media fueling ‘devastating’ kids’ mental health crisis: NGO
The “unchecked expansion” of social media platforms is driving an unprecedented global mental health crisis in kids and teens, a children’s NGO said Wednesday, calling for urgent coordinated action worldwide.
Scientists find unusual build-up of soot-like particles in lung cells of COPD patients
Cells taken from the lungs of people with chronic obstructive pulmonary disease (COPD) have a larger accumulation of soot-like carbon deposits compared to cells taken from people who smoke but do not have COPD, according to a study published in ERJ Open Research. Carbon can enter the lungs via cigarette smoke, diesel exhaust and polluted air.
Weight loss program shown to improve eating disorder symptoms in at-risk people with type 2 diabetes
An intensive low-energy diet program, similar to the “NHS Type 2 Diabetes Path to Remission”, significantly improved eating disorder symptoms in people with type 2 diabetes and excess weight who were at risk of developing eating disorders, according to a University of Oxford study published in The Lancet Psychiatry.
Beards and microbes: What the evidence shows
Beards have long attracted suspicion, sometimes seen as stylish, sometimes as unsanitary. But how dirty are they, really?
Over half of doctors surveyed would consider assisted dying if they had advanced cancer or Alzheimer’s disease
When it comes to advanced cancer or Alzheimer’s disease, over half of doctors would consider assisted dying for themselves, but preferences seem to vary according to their jurisdiction’s legislation on euthanasia, reveal the results of an international survey, published online in the Journal of Medical Ethics.
Researchers call for urgent study of fungal toxins in Ghana’s liver cancer rise
There’s an urgent need to quantify the role of fungal toxins (aflatoxins) found in agricultural crops, such as maize and peanuts (groundnuts), in the escalating rates of liver cancer in Ghana, as well as elsewhere in Africa and Asia, concludes a commentary published in BMJ Global Health.
Newly identified biomarker panel can help assess risk of chronic kidney disease progression in children
Yale School of Medicine researchers have identified a biomarker panel that improves the assessment of chronic kidney disease (CKD) progression in children. Their findings are published in the Journal of the American Society of Nephrology.
Total ankle replacement using unique lateral approach shows good long-term outcomes
A clinical study led by Lew C. Schon, MD, FACS, FAAOS, Director of Orthopedic Innovation at The Institute of Foot and Ankle Reconstruction at Mercy Medical Center, is drawing attention across the orthopedic and biomedical communities for its findings on total ankle replacement surgery.