MAGE-A4 protein promotes tumor progression by suppressing immune responses, mouse study finds

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body’s immune response critical for their elimination. Researchers at Baylor College of Medicine and collaborating institutions have discovered in a mouse model of non-small cell lung cancer that tumors that express protein MAGE-A4 and have lost the Pten gene, a tumor suppressor, accelerate their development and progression into metastasis.

Vitamin E succinate shown to control tumor growth and enhance immunotherapy effects

High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to immunotherapy. In a study recently published in the Proceedings of the National Academy of Sciences, researchers from the University of Chicago Medicine have identified vitamin E succinate (VES) as an effective agent in controlling tumor growth by promoting the degradation of FTO.

New study finds lower cardiovascular risk in type 1 diabetes than in type 2 diabetes

A new study published in the Journal of the Society for Cardiovascular Angiography & Interventions has revealed a lower risk of cardiovascular events for patients with type 1 diabetes (often called juvenile diabetes) than for those with type 2 diabetes. The research highlights the differences between the two types of diabetes and provides new insights that could influence future treatment approaches.

Parental consent law change reduces abortion delays and improves access in Massachusetts

Individuals below the age of 18 are faced with significant barriers when receiving abortion care due to additional parental consent requirements. To address this, the 2020 ROE Act in Massachusetts removed these requirements for minors aged 16–17 years. A new study reveals that this policy change led to a ~60-day decrease in gestational duration at abortion among this age group, highlighting the importance and impact of decreasing barriers to abortion access for minors.