Lab-based study sheds light on the causes of fevers of unknown origin in sub-Saharan Africa

A new retrospective, laboratory-based observational study provides detailed insights into the causes of fevers of unknown origin in sub-Saharan Africa. Together with scientists from Guinea and Slovakia, researchers from the German Center for Infection Research (DZIF) at Charité—Universitätsmedizin Berlin examined 550 patients from Guinea who developed a persistent fever at the time of the major Ebola outbreak in 2014, but tested negative for the Ebola virus on site.

Atopic eczema cases rise, affecting quality of life and health

Cold weather, dry air, an overactive immune system or our modern lifestyle. The causes may vary, but an increasing number of people are suffering from atopic eczema. In particular, children from higher socioeconomic backgrounds are at higher risk of contracting the condition. However, there is help available and it is important to apply treatment early says Laura von Kobyletzki, a researcher at Lund University in Sweden.

Discovery of new mechanism in male sex hormone may lead to safer muscle-strengthening drugs

Researchers have discovered a new mechanism that is used by a male sex hormone essential for muscle and bone function. The findings could lead to the development of new drugs with fewer side effects, for use in applications such as strengthening the muscles of immobile patients. The researchers have published their findings in the journal Cell.

New study reveals how DNA repair genes play a major role in Huntington’s disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington’s disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies. The study is published in the journal Cell.