Machine learning helps identify emergency department patients likely to have health-related social needs

Addressing patients’ health-related social needs such as housing instability, food insecurity, transportation barriers and financial strain is important to improving health outcomes, yet can be challenging. A recent study from Regenstrief Institute and Indiana University Indianapolis Richard M. Fairbanks School of Public Health investigates the best approach to predicting likely need for one or more health-related social need services.

Some viruses prefer mosquitoes to humans, but people get sick anyway. A virologist and entomologist explain why

Humans have an exceptional ability to deal with viruses. In most cases, your immune system is able to fight an infection. On the other hand, your body provides a spa-like environment that is temperate and stable, optimal for viruses to replicate. Human behavior, including close contact with animals and frequent travel, also increases the likelihood of becoming infected.

Disrupting the RBM42 protein could throw a wrench in the gears of cancer’s growth

For decades, scientists have tried to stop cancer by disabling the mutated proteins that are found in tumors. But many cancers manage to overcome this and continue growing. Now, UCSF scientists think they can throw a wrench into the fabrication of a key growth-related protein, MYC, that escalates wildly in 70% of all cancers. Unlike some other targets of cancer therapies, MYC can be dangerous simply due to its abundance.

Lab findings support concept that reducing neuroinflammation could help fight Alzheimer’s

Scientists from DZNE, University Hospital Bonn (UKB) and the University of Bonn provide new evidence that preventing brain inflammation is a promising approach for the treatment of Alzheimer’s disease. Their findings, based on studies in cell culture, mice and tissue samples from patients, may contribute to the development of more effective therapies. They are published in the journal Immunity.