Preterm birth study finds maternal biomarker test significantly reduces neonatal morbidities, improves neonatal outcomes

Preterm birth―defined as delivery before the 37th week of pregnancy—is one of the leading causes of infant deaths in the United States. Babies born prematurely are also at an increased risk of having serious health problems. Yet despite advancements in many areas of obstetrics, little progress has been made to reduce the number of preterm births or improve neonatal outcomes. For the third consecutive year, the March of Dimes Annual Report Card has given the United States a D+ for the country’s persistently high preterm birth rate.

β-glucans show promise as adjuvants for allergy treatment

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of β-glucans. These are natural sugar compounds found in bacteria, fungi and grains. The results indicate that β-glucans can target the immune system and modulate pro-inflammatory responses. Their potential to suppress allergic reactions and offer new approaches to allergy treatment is particularly promising. The research was published in the International Journal of Molecular Sciences.

Detection of poliovirus in EU sewage samples requires enhanced vaccination and increased surveillance: Report

Between September and December 2024, four countries in the EU/EEA (Finland, Germany, Poland, Spain) and the United Kingdom reported detections of circulating vaccine-derived poliovirus type 2 (cVDPV2) in sewage samples. This is the first time cVDPV2 has been detected in EU/EEA countries from environmental surveillance.

Scientists identify mechanism for self-repair of thymus, a crucial component of the immune system

A team of international researchers led by scientists at City of Hope have demonstrated a way to boost thymic function after damage in preclinical studies. The team’s study results, published today in the journal Immunity, outline their discovery of a specific type of regulatory T cell that can home back into the thymus and repair the organ when it’s damaged.