Couples help researchers discover gene that may afford protection against COVID-19

During the COVID-19 pandemic, health worker Maria Tereza Malheiros Sapienza’s curiosity was aroused by her immunity to SARS-CoV-2: her husband, Marcelo Sapienza, a physician, was infected twice (in April 2020 and January 2022), but she remained perfectly well and asymptomatic even though she was in direct contact with him prior to both infections.

Integrating palliative and dementia care can cut emergency visits and hospitalizations in half

IN-PEACE, which provides palliative care integrated with state-of-the-art dementia care to patients with dementia and their caregivers, cut in half the number of emergency department visits and hospitalizations of study participants. African American individuals and those with lower incomes benefited the most in reduction of use of these medical facilities.

‘Hallmarks of cancer’ offer new perspective on malignant transformation and tumor growth

“What is a tumor?” This is the fundamental question to answer if we want to treat cancer effectively. Our vision of cancer and tumors has been evolving with time, from the simplistic bunch of all-similar malignant cells to a more sophisticated, heterogeneous and hierarchical cellular structure, composed of many different cell types. Recently, a new paradigm has emerged: the hallmarks of cancer.