Researchers from Mass General Brigham and collaborating institutions have developed a non-invasive approach to manipulate cardiac tissue activity by using light to stimulate an innovative ink incorporated into bioprinted tissue. Their goal is to develop a technique that can be used to repair the heart. Their findings in preclinical models, published in Science Advances, show the transformative potential of non-invasive therapeutic methods to control electrically active tissues.
Smoke alarm triggers evacuation at Maina Soko Medical Centre
MAINA Soko Medical Centre says it today experienced an automatic smoke alarm activation, prompting the evacuation of all patients and staff to the fire assembly point as a precautionary measure. In a statement, Maina Soko Medical Centre Commandant, Brigadier General Levy Muchemwa, disclosed that data from the monitoring system in the control room indicated smoke […]
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VR subway experiment highlights role of sound in disrupting balance for people with inner ear disorder
The vestibular system is a network of organs in the inner ears that detects the motions and position of the head. The brain uses this information, along with inputs from the eyes and joints, to maintain the body’s balance.
Study highlights pharmacovigilance challenges in CAR T-cell therapies, suggests specific assessment criteria
Cases of secondary tumors have been reported as a possible adverse reaction to the treatment of certain blood cancers with CAR T-cells. A recent analysis of the cases reported to the Paul-Ehrlich-Institut highlights the challenges in the assessment of these newly diagnosed T-cell diseases. The result: in order to better assess these rare but serious cases and identify possible risk factors, CAR T-cell-specific assessment criteria should be defined in pharmacovigilance activities and specific molecular test methods should be established. These steps will further increase patient safety.
Study finds OCD patients’ decision making mirrors general population
Although obsessive compulsive disorder (OCD) can be treated, research has shown that people with the disorder tend to have a lower quality of life than neurotypical people. Many struggle to achieve the same levels of education and financial stability as people without the disorder.
Scientists uncover how cancer cells hijack T-cells, making it harder for the body to fight back
Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune system. It essentially hacks the immune cells, transferring its own faulty mitochondrial DNA (mtDNA) into the T-cells meant to attack it.
Lower dexamethasone dose does not impair survival in multiple myeloma
For patients with newly diagnosed multiple myeloma (NDMM) receiving dexamethasone induction, dose reductions do not negatively impact survival, according to a study published online Jan. 2 in Blood.
Targeting potassium channel shows promise for treating brain tumors in children
Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumor in children.
Using AI to predict the after-effects of brain tumor surgery
Patients with a glioma, a type of malignant brain tumor, can suffer from cognitive problems after surgery. However, the true effect of surgery on complex cognitive tasks is not known. To predict the effects of surgery on cognitive tasks, Ph.D. researcher Lars Smolders developed an AI model that utilizes information about neural connections in the brain extracted from the patient’s MRI images before surgery.
Mapping the brain’s self-healing abilities after stroke
A new study by researchers at the Department of Molecular Medicine at SDU sheds light on one of the most severe consequences of stroke: damage to the brain’s “cables”—the so-called nerve fibers—which leads to permanent impairments. The study, published in The Journal of Pathology, which is based on unique tissue samples from Denmark’s Brain Bank located at SDU, may pave the way for new treatments that help the brain repair itself.