Light-activated ink developed to remotely control cardiac tissue to repair the heart

Researchers from Mass General Brigham and collaborating institutions have developed a non-invasive approach to manipulate cardiac tissue activity by using light to stimulate an innovative ink incorporated into bioprinted tissue. Their goal is to develop a technique that can be used to repair the heart. Their findings in preclinical models, published in Science Advances, show the transformative potential of non-invasive therapeutic methods to control electrically active tissues.

Smoke alarm triggers evacuation at Maina Soko Medical Centre

MAINA Soko Medical Centre says it today experienced an automatic smoke alarm activation, prompting the evacuation of all patients and staff to the fire assembly point as a precautionary measure. In a statement, Maina Soko Medical Centre Commandant, Brigadier General Levy Muchemwa, disclosed that data from the monitoring system in the control room indicated smoke […]

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Study highlights pharmacovigilance challenges in CAR T-cell therapies, suggests specific assessment criteria

Cases of secondary tumors have been reported as a possible adverse reaction to the treatment of certain blood cancers with CAR T-cells. A recent analysis of the cases reported to the Paul-Ehrlich-Institut highlights the challenges in the assessment of these newly diagnosed T-cell diseases. The result: in order to better assess these rare but serious cases and identify possible risk factors, CAR T-cell-specific assessment criteria should be defined in pharmacovigilance activities and specific molecular test methods should be established. These steps will further increase patient safety.

Using AI to predict the after-effects of brain tumor surgery

Patients with a glioma, a type of malignant brain tumor, can suffer from cognitive problems after surgery. However, the true effect of surgery on complex cognitive tasks is not known. To predict the effects of surgery on cognitive tasks, Ph.D. researcher Lars Smolders developed an AI model that utilizes information about neural connections in the brain extracted from the patient’s MRI images before surgery.

Mapping the brain’s self-healing abilities after stroke

A new study by researchers at the Department of Molecular Medicine at SDU sheds light on one of the most severe consequences of stroke: damage to the brain’s “cables”—the so-called nerve fibers—which leads to permanent impairments. The study, published in The Journal of Pathology, which is based on unique tissue samples from Denmark’s Brain Bank located at SDU, may pave the way for new treatments that help the brain repair itself.