Mental well-being and physical activity can form a positive cycle for older adults

According to a recent study published in BMC Public Health, the tendency to experience positive affectivity contributed to people being physically active or even increasing their activity during the COVID-19 restrictions. In contrast, depressive feelings were linked to lower physical activity. The results suggest that mental well-being can help maintain a physically active lifestyle. Mental well-being and physical activity may thus form a positive cycle.

Public policies are needed to improve brain health, researchers urge in commentary

An estimated 3.4 billion people—43% of the world population—had a condition affecting the nervous system in 2021, leading to 11.1 million deaths. Increasing numbers of people affected by stroke, dementia and late-life depression—the three major disorders of the aging brain—foreshadow a “gray tsunami” that requires a new national commitment to address brain health, according to a new commentary published this week in Circulation.

Team develops weight loss app that tracks fiber, protein content in meals

Many people struggle to maintain a healthy weight, and choosing the optimal meals for weight loss can be challenging. A research team at the University of Illinois Urbana-Champaign has developed a weight management program that helps individuals plan meals with the assistance of a web application and support from a registered dietitian. In a study published in JMIR Formative Research, they discuss the app’s features, development, and implementation.

Autism practitioners move beyond traditional demographics toward adaptive environments

At the grocery store, a mother guides her child down the cereal aisle. Nearby, a man studies a list on his phone while a cashier rings up a customer’s order with precision. Amid these ordinary scenes, there is likely someone who is autistic. One in 36 people have a diagnosis of autism, a prevalence higher than many realize. Contributing to this gap in understanding are outdated perceptions and limited diagnostic frameworks.

Personalized therapy for rare genetic diseases: Patient-derived organoids offer new hope

Children’s Mercy Kansas City has achieved a significant advancement toward the treatment of rare genetic diseases through the use of personalized antisense oligonucleotides (ASOs). This innovative approach has shown promising results in preclinical evaluations, which offers new hope for patients with previously untreatable conditions and validates personalized therapies for patients in only eight weeks, significantly faster and more cost-effective than the industry average.