New dual stem cell therapy developed to treat brain metastasis in patients with non-small cell lung cancer

New research highlights the promise of a novel stem cell treatment strategy for leptomeningeal brain metastasis (LBM), a severe form of metastatic brain cancer that spreads to membranes surrounding the brain and spinal cord and occurs in up to 20% of people with cancer. The researchers say their findings in newly developed preclinical models of metastatic non-small cell lung cancer (NSCLC) support pursuing clinical trials for this treatment strategy.

Research identifies gut microbes that offer potential for personalized nutrition strategies

Gut microbial metabolism of L-carnitine, leading to the production of trimethylamine N-oxide (TMAO), links red meat consumption to cardiovascular risks. Microbial genes, including cntA/B, the cai operon, and the gbu gene cluster, have been implicated in converting L-carnitine into TMA(O). However, the key genes and microbes remain underexplored.

Cancer survivors face steep costs for essential medical equipment

A University of Minnesota Medical School research team has examined the financial burden of different medical services—including outpatient care, inpatient care, prescription drugs and physical therapy—on cancer survivors. Of all these medical services, the research team found medical equipment results in the highest percentage of out-of-pocket costs, including wheelchairs, canes, hearing aids and oxygen equipment, among other items.