For patients with resectable esophageal adenocarcinoma, perioperative chemotherapy with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) leads to improved survival compared with preoperative chemoradiotherapy, according to a study published in the Jan. 23 issue of the New England Journal of Medicine.
Uncovering the role of Y chromosome genes in male fertility in mice
Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don’t produce enough sperm and are infertile.
Long COVID symptoms linger: Study shows no major changes in second year
Two-thirds of people with post-COVID-19 syndrome have persistent, objective symptoms—including reduced physical exercise capacity and reduced cognitive test performances—for a year or more, with no major changes in symptom clusters during the second year of their illness, according to a study published January 23 in PLOS Medicine by Winfried Kern of Freiburg University, Germany, and colleagues.
Child mortality in England has risen since pandemic, study finds
While child deaths in England fell temporarily during the COVID-19 pandemic, they have now risen to new heights, a new study from researchers at the University of Bristol and based on unique National Child Mortality Database (NCMD) data has found.
Researchers track sharp increase in diagnoses for sedative, hypnotic and anxiety use disorder in young adults
The prevalence of diagnosed disorders from recurrent use of sedative, hypnotic and antianxiety medications in adolescents and young adults has increased sharply since 2001, according to Rutgers Health researchers.
Racial disparities in opioid prescriptions persist despite socioeconomic factors
Non-white communities had significantly less access to opioid medications commonly prescribed for moderate to severe pain than white communities over the decade beginning in 2011, according to a study by Weill Cornell Medicine researchers.
Intranasal oxytocin shows promise for treating core symptom of frontotemporal dementia
A new study led by Western researchers found frequent treatment with intranasal oxytocin—a hormone in the brain associated with empathy—offers promise for addressing a key symptom among patients with frontotemporal dementia (FTD): Apathy.
Death toll from Tanzania Marburg outbreak rises to nine
An outbreak of the Marburg virus has killed nine people in Tanzania, Africa’s health agency said Thursday, up from eight suspected deaths reported by the World Health Organization last week.
Meet phosphine, a gas commonly used for industrial fumigation that can damage your lungs, heart and liver
In 1980, two children and 29 crew members aboard a grain freighter became ill. They had been exposed to phosphine—a chemical used in fumigation to kill pests in and on grain—for four days. In the end, one child died.
Not just a data highway: Spinal cord is also a processor of sensory stimuli, study shows
In a new study, scientists at the Leibniz Institute for Neurobiology (LIN) and University Hospital Magdeburg demonstrated that the spinal cord is far more than just a transmission pathway that transmits sensory stimuli from the body. Instead, sensory stimuli are processed in the spinal cord before reaching the brain.