Study finds smoking opioids is associated with lower mortality than injecting but is still high-risk

A new study published in Addiction has found that opioid smoking appears to be associated with lower mortality risk compared with opioid injecting. The authors, however, caution that opioid smoking still carries a substantial overdose risk and that these results should not be interpreted as suggesting that opioid smoking is safe.

Risk preference is governed by different hypothalamus–habenula circuits, study finds

To survive in complex and unpredictable environments, humans and other animals need to learn to predict the consequences of their actions, so that they can reduce risks and maximize their gains. In humans, this risk evaluation process is known to be highly sophisticated and is applied daily to a wide range of situations beyond life-and-death scenarios.