By studying biomarkers known to be involved in gastrointestinal cancers, researchers at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a biomarker algorithm that, when combined with a noninvasive method to collect esophageal cells for study, could give clinicians insight into which patients [SJMM1] have esophageal cancer or precancerous conditions such as Barrett’s esophagus (BE) or high-grade dysplasia. Typically, such determinations are made by endoscopy, an invasive procedure performed with patients under anesthesia.
Protein-coding transcript sheds light on Alzheimer’s disease risk across genetic types
Late-onset Alzheimer’s disease is a debilitating, progressive neurodegenerative disease that affects about 7 million Americans, a figure that is expected to nearly double by 2050, according to the Alzheimer’s Association. While there is no cure for the disease, early detection and treatment can preserve brain function for longer.
Novel PET approach identifies early signs of pulmonary arterial hypertension
A new molecular imaging technique—18F-FAPI PET—can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach has the potential to pave the way for more personalized management of PAH, offering more timely interventions to improve patient prognosis.
Multiple sclerosis linked to higher risk of mental illness during and after pregnancy
People with multiple sclerosis (MS) face a significantly higher risk of perinatal mental illness compared to those with other chronic conditions, according to a new study analyzing over 890,000 births in Ontario.
Discovery reveals birth’s impact on neural stem cell maintenance
A research group from Nagoya City University has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).The findings of the study are published in Science Advances.
Who to vaccinate first? Engineers answer a life-or-death question with network theory
Engineering and medical researchers at Penn have developed a framework that can determine the best and most computationally optimized distribution strategy for COVID-19 vaccinations in any given community.
Adult children of divorced parents at higher risk of stroke, study finds
A recent study by researchers from the University of Toronto, Tyndale University and the University of Texas at Arlington found that older adults are at greater risk of having a stroke if they experienced their parents divorcing during childhood.
Trump-era HHS website makes term ‘abortion’ harder to find
Abortion information is disappearing from federal government websites, signaling potential changes in abortion under the second Trump administration.
Ultrasensitive test detects and serially monitors intact virus levels in COVID-19 patients
Investigators from Mass General Brigham have found that a method originally designed for cancer detection can also identify and monitor even tiny amounts of SARS-CoV-2 intact viral particles in blood and other fluids from patients with acute COVID-19 infections, creating the potential for guiding future treatment of patients.
Why a common asthma drug will now carry extra safety warnings about depression
Australia’s Therapeutic Goods Administration (TGA) recently issued a safety alert requiring extra warnings to be included with the asthma and hay fever drug montelukast.