Biomarker algorithm for Barrett’s esophagus and esophageal cancer developed

By studying biomarkers known to be involved in gastrointestinal cancers, researchers at the Johns Hopkins Kimmel Cancer Center and the Johns Hopkins University School of Medicine have developed a biomarker algorithm that, when combined with a noninvasive method to collect esophageal cells for study, could give clinicians insight into which patients [SJMM1] have esophageal cancer or precancerous conditions such as Barrett’s esophagus (BE) or high-grade dysplasia. Typically, such determinations are made by endoscopy, an invasive procedure performed with patients under anesthesia.

Novel PET approach identifies early signs of pulmonary arterial hypertension

A new molecular imaging technique—18F-FAPI PET—can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach has the potential to pave the way for more personalized management of PAH, offering more timely interventions to improve patient prognosis.