All posts by : Felistas

Researchers at University of Tsukuba conducted a detailed investigation on exercise-induced arterial adaptations (changes in arterial structure and function associated with sport-specific demands) among college baseball players.

A new Health Affairs article highlights the detrimental impact of recent state and federal policies that restrict discussions of “divisive concepts,” including structural racism. It warns that these policies undermine efforts to address health inequities and improve population health.

Megakaryocytes (MKs), known for their role in platelet production, have emerged as critical players in immune responses, showcasing versatility in both physiological and pathological contexts. Recent advances in technology have unveiled the diverse immune functions of MKs, which express immune sensors and participate in immune activities, thus expanding their traditional role beyond hemostasis and coagulation.

Bone pain. Joint pain. Bone swelling. These are symptoms that about 1,000 people in the United States begin to feel each year shortly before being diagnosed with osteosarcoma, a type of cancer that starts in the bones. Although any age can develop osteosarcoma, approximately half of diagnosed cases are in children and adolescents.

For Medicaid beneficiaries with schizophrenia, delivery of mental health care through telehealth (telemental health care) diffused rapidly after onset of the COVID-19 pandemic, according to a study published online Jan. 16 in JAMA Network Open.

Despite the success cardiac rehabilitation has shown at reducing heart-related deaths and hospital readmissions, higher out-of-pocket costs may prevent patients from participating in the program, a Michigan Medicine study suggests.

Cancer remains one of the most complex diseases, with its diverse molecular profiles and cellular compositions posing significant challenges for treatment. Traditional methods of cancer research, such as two-dimensional cell cultures and animal models, often fail to capture the full complexity of human cancers, particularly the three-dimensional structures and microenvironmental interactions of solid tumors.

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication. A recent study published in eGastroenterology introduces young rabbits with CF as a novel and accessible model to study CF-related pancreatic endocrine pathology. This model offers an unprecedented opportunity to deepen our understanding of CF-related diabetes (CFRD), a condition affecting up to 50% of adults with CF.

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection.

Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme—P4HA1 prolyl hydroxylase, is strongly induced in CD8+ T cells in solid cancer, the primary immune cells involved in combating cancer. P4HA1 causes disruptions in energy production within the cells, which leads to weaker immune cells that are less able to fight cancer and form long-lasting anti-cancer immunity, highlighting P4HA1 as a promising target for treating solid tumors.