All posts by : Felistas

A study led by the UAB has analyzed the brains of women during pregnancy for the first time using neuroimaging techniques. The study included non-pregnant mothers, whose partners were pregnant, to distinguish biological effects from those caused by the experience of being a mother. The research shows that there is a reduction and partial recovery of almost 5% of gray matter in 94% of the total gray matter volume of the brain, especially in regions linked to social cognition.

The search for answers to Alzheimer’s disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University’s Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

In the open-label phase 2 LITESPARK-003 study, led by Dana-Farber Cancer Institute’s Toni Choueiri, MD, researchers investigated for the first time the combination of cabozantinib, an anti-angiogenic agent, plus belzutifan, a first-in-class HIF-2α inhibitor. The findings are published in The Lancet Oncology journal.

Neural network models that are able to make decisions or store memories have long captured scientists’ imaginations. In these models, a hallmark of the computation being performed by the network is the presence of stereotyped sequences of activity, akin to one-way paths. This idea was pioneered by John Hopfield, who was notably co-awarded the 2024 Nobel Prize in Physics. Whether one-way activity paths are used in the brain, however, has been unknown.

A completely new way of treating type 1 diabetes is being tested at Uppsala University Hospital. Patients are being offered transplants of genetically modified insulin-producing cells and the initial results are promising. We put a few questions to Per-Ola Carlsson, Professor of Medical Cell Biology, who is leading the study.

Researchers at the University of Kentucky’s Sanders-Brown Center on Aging are at the forefront of advancing dementia research with groundbreaking work on a condition known as LATE, or “limbic predominant age-related TDP-43 encephalopathy.”

Appropriate use criteria (AUC) for the use of amyloid and tau positron emission tomography (PET) have been issued by the Alzheimer’s Association and the Society for Nuclear Medicine and Molecular Imaging and published online Jan. 8 in both Alzheimer’s & Dementia and the Journal of Nuclear Medicine.

Following an extensive scientific review, the U.S. Food and Drug Administration has authorized the marketing of 20 ZYN nicotine pouch products. Nicotine pouches—small synthetic fiber pouches containing nicotine—are designed to be placed between a person’s gum and lip.

Poor mental health was increasingly prevalent from 2011 to 2022, with inequities discernible by age, sex, and racial and ethnic group, according to a research letter published online Jan. 15 in JAMA Network Open.

Intensive care units (ICUs) face mounting pressure to effectively manage resources while delivering optimal patient care. Groundbreaking research published in the journal Information Systems Research highlights how a novel artificial intelligence (AI) model is revolutionizing ICU care by not only improving predictions of patient length of stay, but also equipping clinicians with clear, evidence-based insights to guide critical decisions.