Study reveals immune system changes linked to schizophrenia and treatment resistance

Researchers from Singapore’s National Healthcare Group (NHG)’s Institute of Mental Health (IMH) and Agency for Science, Technology and Research (A*STAR) have made strides in understanding the connection between the immune system and resistance to antipsychotic medications in schizophrenia, using changes in immune cell populations to predict potential treatment resistance and initiate the most appropriate treatment sooner.

Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials

A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made “exciting,” patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors. This emerging technology holds promise for very safe and more effective treatment of cancers with high mortality rates, including liver, ovarian and metastatic breast cancer.

Research using non-toxic bacteria to fight high-mortality cancers prepares for clinical trials

A University of Massachusetts Amherst-Ernest Pharmaceuticals team of scientists has made “exciting,” patient-friendly advances in developing a non-toxic bacterial therapy, BacID, to deliver cancer-fighting drugs directly into tumors. This emerging technology holds promise for very safe and more effective treatment of cancers with high mortality rates, including liver, ovarian and metastatic breast cancer.

TLE6 identified as a protein associated with infertility in male mice

Genetic changes are a significant cause of infertility, impacting over 15% of the global population. TLE6, a major protein involved in early embryonic development, is known to affect female fertility. In a recent study, researchers unraveled its role in male fertility using a novel Tle6-deficient mouse model. Abnormal sperm morphology with a marked reduction in sperm count and motility highlighted the role of Tle6 in sperm function and production, and its potential association with male infertility.