New genetic risk factors for depression have been identified across all major global populations for the first time, allowing scientists to predict the risk of depression regardless of ethnicity. The study is published in the journal Cell.
Circulation problems in brain’s temporal lobes linked to mild cognitive impairment in older adults
Mild cognitive impairment is linked to blood vessel dysfunction in the brain’s temporal lobes—the seat of memory—according to a new USC-led study.
Scientists uncover rapid-acting, low-side-effect antidepressant target
The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, including slow action and adverse effects with long-term use. This underscores the urgent need for novel, rapidly-acting therapeutic agents with minimal side effects.
Why some osteoporosis drugs may protect against COVID-19
Researchers have provided the molecular explanation for why some osteoporosis drugs offer protection against COVID-19.
Gene editing extends lifespan in mouse model of prion disease
Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50% in a mouse model of the fatal neurodegenerative condition. The treatment, which uses base editing to make a single-letter change in DNA, reduced levels of the disease-causing prion protein in the brain by as much as 60%.
Early life stress alters brain metabolism differently in male and female mice, study reveals
Early life stress (ELS) can have long-lasting effects on mental health, increasing the risk of developing anxiety disorders and post-traumatic stress disorder (PTSD). Importantly, women are disproportionately affected by PTSD, highlighting the need to understand how biological sex influences responses to trauma.
Study links PFAS contamination of drinking water to a range of rare cancers
Communities exposed to drinking water contaminated with manufactured chemicals known as per- and polyfluoroalkyl substances (PFAS) experience up to a 33% higher incidence of certain cancers, according to new research from the Keck School of Medicine of USC.
Commonly prescribed medications can increase fall risk and related injuries in people with COPD
People with COPD experience more falls and related injuries requiring medical care when using common fall-risk increasing drugs, according to a recent study. The research is published in Chronic Obstructive Pulmonary Diseases: Journal of the COPD Foundation.
Will we have fewer doctors of color?
Medical schools have experienced a steep decline in enrollment among Black and Hispanic students since the Supreme Court banned the consideration of race in admissions.
FDA adds warning label to RSV vaccines Abrysvo and Arexvy about the risk for Guillain-Barré syndrome
The U.S. Food and Drug Administration now requires and has approved safety labeling changes to the prescribing information for the Abrysvo (Pfizer) and Arexvy (GlaxoSmithKline) respiratory syncytial virus (RSV) vaccines to include warnings and precautions about the risk for Guillain-Barré syndrome (GBS).