Immunofluorescence study sheds light on brain’s DNA damage and repair processes

Brain cells receive sensory inputs from the outside world and send signals throughout the body telling organs and muscles what to do. Although neurons comprise only 10% of brain cells, their functional and genomic integrity must be maintained over a lifetime. Most dividing cells in the body have well-defined checkpoint mechanisms to sense and correct DNA damage during DNA replication.

Mice’s sex-based social preferences shift under stress: Dopamine circuits play crucial role

Researchers from Xi’an Jiaotong University and collaborating institutions in China have identified sexually dimorphic dopamine (DA) circuits in the brain that influence sociosexual preferences in mice. They found innate preferences for social interactions with female mice are reversed under survival stress, with both male and female mice switching to male preference.

Study finds opioid pain medications very infrequently prescribed to NFL players

Due to the physical contact nature of their occupation, the elite athletes of the National Football League (NFL) often experience pain. However, an analysis of 2021 and 2022 data from the National Football League Prescription Drug Monitoring Program shows that team members in those two years were even less likely than both the general U.S. population and males of similar age living in the U.S., to have a prescription for an opioid pain medication.