For overweight or obese individuals without diabetes, but with pre-existing cardiovascular disease, semaglutide (Ozempic, Wegovy) is not cost-effective at current pricing, new research shows. However, with price reductions or rebates up to 50%, it could meet the benchmark for value in health care.
Study finds women are less likely to get a lung transplant than men, spend six weeks longer on waiting list
Women are less likely to receive a lung transplant and spend an average of six weeks longer on the waiting list, according to a study published in ERJ Open Research. However, women who receive a lung transplant are more likely than men to live for five years post-transplant. Based on their findings, the researchers encourage changes in regulation and clinical guidelines to address this inequality.
Mapping cells that tune in to sound: Researchers identify major neurons involved in hearing process
When we hear sounds, specialized cells in the cochlear nucleus are the first to process that information, enabling our brains to understand speech, enjoy music and recognize various noises. For decades, this area has been known to be a vital part of the auditory system; however, specific cell populations responsible for processing different sounds within the cochlear nucleus have not fully been understood or classified.
Scientists reveal genetic drivers of metastasis across multiple cancer types
Cancer metastasis—the spread of cancer to other organs—is the leading cause of death among cancer patients. Researchers have now uncovered a “genetic signature” of 177 genes shared across multiple cancer types that drives this deadly process.
Access to care: Five principles for action on primary health-care teams
Primary care is in crisis. Recent estimates indicate 6.5 million Canadians, including 2.5 million Ontarians, do not have a primary care provider.
New tool puts reproductive risk for BRCA carriers into perspective
“I just wish someone had told me this was a possibility.” Kara Maxwell distinctly remembers the moment she heard those words eight years ago from the mother of a child with Fanconi anemia (FA). Maxwell met her at a conference focused on the rare, recessive genetic bone marrow disorder that causes myriad medical challenges, including childhood cancer. While survival is improving, the average lifespan for FA is currently only 20 to 30 years.
Exercising after breakfast curbs blood sugar spikes and appetite in women
Researchers at the University of Toronto have found that in healthy females, a post-meal rise in blood sugar was lower if they waited until after breakfast to exercise.
3D printed scaffolding to rebuild jaw bones: Clinicians have success using custom design
Clinicians have successfully used custom-made 3D printed bone scaffolds, printed on-site at The University of Queensland, to rebuild part of a man’s jawbone.
Banning social media won’t fix Australia’s youth mental health crisis, say researchers
Mental illness in Australian youth is rising. We don’t know why, but despite very little evidence, social media is bearing the brunt of the blame.
Tuberculosis research: Scientists demonstrate effectiveness of a new antibiotic
A consortium including scientists from the Tropical Institute at LMU University Hospital has demonstrated the effectiveness of a new antibiotic. Tuberculosis is the most common infectious disease worldwide. In the year 2022 alone, there were 10.6 million new infections and 1.3 million deaths.