Trametinib, a mitogen-activated protein kinase (MEK) inhibitor, reduces mortality and morbidity in children with severe hypertrophic cardiomyopathy (HCM) caused by pathogenic variants in the RAS/MAPK pathway, according to a study published in JACC: Basic to Translational Science.
Wastewater treatment plant testing reveals limited removal of organofluorines, putting millions at potential risk
A research team led by Harvard University has found elevated concentrations of organofluorine in U.S. municipal wastewater. More than 60% consisted of widely prescribed fluorinated pharmaceuticals, while 6 federally regulated perfluoroalkyl and polyfluoroalkyl substances (PFAS) made up less than 10% of total extractable organofluorine in samples.
Is the world ready for the next pandemic?
An awkward question remains five years after COVID-19 began its deadly rampage: is the world ready to handle the next pandemic?
Genetically modified mosquitoes may curb disease with ‘toxic’ semen
Genetically engineered mosquitoes with toxic semen could be a new weapon against tropical disease, Australian scientists said after trialing the novel pest control method.
Second pig heart transplant patient offers vital lessons
Continuing significant advancements in the field of xenotransplantation, surgeon-scientists from the University of Maryland School of Medicine provided an extensive analysis on the second patient in the world to receive a genetically-modified pig organ.
Study finds job strain compromises long-term sleep quality
In a study published in the American Journal of Industrial Medicine, middle-aged workers in the U.S. who reported high job strain at the start of the study experienced significantly more sleep disturbances over an average follow-up of nine years.
Staying safe in a wildfire: What to pack and when to evacuate
Evacuating a wildfire area can be scary, but experts say people can significantly improve their own safety with a little preparation and common sense.
Forgotten but not gone: COVID keeps killing, five years on
Five years since COVID-19 started upending the world, the virus is still infecting and killing people across the globe—though at far lower levels than at the height of the pandemic.
Morning coffee may protect the heart better than all-day coffee drinking, study suggests
People who drink coffee in the morning have a lower risk of dying from cardiovascular disease and a lower overall mortality risk compared to all-day coffee drinkers, according to research published in the European Heart Journal.
Ready to quit vaping in the new year? Study uncovers the best ways
A new study, co-led by a University of Massachusetts Amherst researcher, set out to identify the most effective strategies for helping people quit vaping. The findings, published in the Cochrane Database of Systematic Reviews, suggest that varenicline, a prescription medication often used to help people stop smoking, and text message-based interventions can help people quit.