In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent. This crystalline arthritis is caused by calcium pyrophosphate (CPP) crystal deposition in joints. The findings of this novel study in the Annals of the Rheumatic Diseases, open up promising new avenues for targeted prevention and treatment of CPPD disease, which are currently lacking.
AI can assess infant brain maturity in minutes
Machine-learning algorithms can now estimate the “brain age” of infants with unprecedented precision by analyzing electrical brain signals recorded using electroencephalography (EEG).
Study: 1 in 3 youth with mental health crisis spends over 12 hours in emergency department waiting for psychiatric bed
Approximately 1 in 3 pediatric mental health Emergency Department (ED) visits resulting in admission or transfer exceeded 12 hours, and over 1 in 8 exceeded 24 hours, according to estimates based on nationally representative data from 2018 to 2022. Seven in 10 of all kids staying in the ED over 12 hours were there for suicidal thoughts or attempts, and over half for aggressive behaviors.
Amid measles outbreak, Texas is poised to make vaccine exemptions for kids easier
Texas this year has been the center of the nation’s largest measles outbreak in more than two decades, as a mostly eradicated disease has sickened more than 700 in the state, sent dozens to hospitals and led to the death of two children who were unvaccinated.
Original COVID-19 vaccination did not stop immune system from fighting variants, finds study
Prior COVID-19 vaccination did not stop the immune system from mounting a protective response to the delta and omicron strains, though new mutation-specific antibody production dipped slightly, according to a study led by researchers at the University of Arizona Health Sciences and published in Nature Immunology.
Sugary drinks, processed foods, alcohol and tobacco are big killers: Why the G20 should add its weight to health taxes
By 2030, non-communicable diseases will account for 75% of all deaths annually. Eight percent of these will be in the global south. Most of these diseases are what we call silent killers: type 2 diabetes, high blood pressure and heart disease, as well as certain types of cancer at increasingly younger ages.
Researchers investigate the cause of lung damage in autoimmune diseases
Patients with systemic sclerosis or Sjögren’s syndrome suffer from various inflammatory reactions triggered by the body’s own immune system. A team of researchers has investigated the role of certain immune cells in the pathogenesis of systemic sclerosis and Sjögren’s syndrome. They recently published their findings in the journal Rheumatology.
AI faces skepticism in end-of-life decisions, with people favoring human judgment
The role of AI in medical decision-making elicits different reactions in people when compared with human doctors. A new study investigated the situations where the acceptance differs and why with stories that described medical cases.
Parent-mediated intervention found to be beneficial for toddlers who are deaf
A parent-mediated intervention (PMI) is beneficial for child communication outcomes in children who are deaf or hard of hearing (DHH), according to a study published online May 27 in Pediatrics.
For opioid addiction, treatment underdosing can lead to fentanyl overdosing: A physician explains
Imagine a patient named Rosa tells you she wakes up night after night in a drenching sweat after having very realistic dreams of smoking fentanyl.