Genetic investigations reveal reason for severe neuropathy after infection

Neuropathy, a disorder in which damage to nerves can impair sensation and movement, has many causes, including infection. Now, researchers from the UK have identified distinct genetic changes in a newly-discovered neuropathy and believe that their work will provide insights into the causal mechanism and why some previously healthy people develop neuropathies after infection whereas others do not.

Intravenous tenecteplase beneficial before endovascular thrombectomy

For patients with acute ischemic stroke due to large-vessel occlusion who present within 4.5 hours, intravenous tenecteplase before endovascular thrombectomy is associated with higher functional independence at 90 days, according to a study published online May 21 in the New England Journal of Medicine to coincide with the annual European Stroke Organisation Conference, held from May 21 to 23 in Helsinki.

Long-term remission of advanced liver cancer in 46% of patients achieved with combination therapy

An interdisciplinary research team has demonstrated a durable and lasting response to a novel treatment—combined locoregional therapy and immunotherapy (LRT-IO)—for advanced liver cancer patients. The study marks the first investigation into the long-term outcomes for patients with locally advanced liver cancer receiving this treatment. The researchers identified key factors associated with a complete response, and found that this pioneering approach is safe, effective and sustainable.

Working women are too often left to deal with endometriosis alone. But big changes could be coming

Endometriosis is a long-term and invisible gynecological condition that affects around 1.5 million women in the UK alone. It’s known for its unpredictable and debilitating symptoms, like chronic pelvic pain, heavy periods and fatigue. But many women face outdated practices in the workplace that just don’t accommodate the reality of the condition.