Venous thromboembolism in children: Rivaroxaban found effective and safe even with extended use

Venous thromboembolism (VTE) is a life-threatening complication in children with serious underlying conditions such as heart defects or cancer. Treatment or prevention of thrombosis poses an additional challenge in everyday clinical practice. A therapy using the active ingredient rivaroxaban specifically tailored to children was successfully tested for the first time in 2020.

Muscle quality may hold clues to early cognitive decline

Over the past decade, much research has focused on the connection between skeletal muscle health and cognitive disorders. Scientists have found that sarcopenia, a geriatric syndrome characterized by progressive loss of skeletal muscle mass and function, appears to be strongly associated with an elevated risk of dementia. The complex relationship between our muscles and brain health represents a promising frontier in preventive medicine, particularly as global populations continue to age.

Activation of receptors involved in gut microbial breakdown of fiber may cut heart disease risk by up to 20%

A Monash University study of almost 400,000 people, published in the journal Cardiovascular Research , is the first to indicate, in humans, that the signaling of substances called short-chain fatty acids or SCFAs, released when gut bacteria break down dietary fiber, significantly protects against cardiovascular disease and hypertension by up to 20%.