In a comprehensive research study, scientists have uncovered a previously unknown mechanism explaining how neurons survive botulinum neurotoxin type A (BoNT/A) exposure, despite the toxin’s powerful ability to block neurotransmission.
Reducing wait times for hip and knee replacement surgeries
How can wait times for much-needed hip and knee replacement surgery be reduced in Canada? Coordinated referral and team-based care models show promise, according to research published in the Canadian Medical Association Journal.
Majority of youth overdose deaths from 2018 to 2022 were driven by fentanyl alone, study reveals
Fatal drug overdoses among youth aged 15 to 24 in the United States involving synthetic opioids alone—not mixed with other substances—soared by 168% over the five-year time period from 2018 to 2022, a study shows. Published online in the journal Pediatrics, the work also found that youth overdose rates and drug combinations varied significantly across age, sex and race/ethnicity.
Vaping increases dependency more than nicotine gum, study finds
A paper published in Nicotine and Tobacco Research finds that pod-style electronic cigarette devices are more addictive than nicotine gum, indicating that such devices have a very high potential for abuse.
Could clinician entrepreneurs benefit Canada’s health and economy?
Clinical entrepreneurs—physicians, nurses, and other health care professionals—who understand Canada’s health care challenges first-hand could help improve the health system and grow the economy, argue two physicians in a commentary published in the Canadian Medical Association Journal.
Study links residual inflammation in psoriasis patients to obesity and fatty liver disease
New research shows that in patients with psoriasis, even though their skin responds well to treatment with biologics, inflammation can linger, leading to broader health implications such as obesity and cardiovascular and fatty liver disease.
A new tool can help predict brain-damaging seizures and free up continuous EEG machines for high-risk patients
In hospital intensive care units, neurologists often use a simple scorecard to quickly evaluate a critically ill patient’s likelihood of having a brain-damaging seizure so they can prevent it. The scorecard saves lives, lowers costs and helps doctors make far more efficient use of important, expensive medical equipment.
Cancer during young adulthood carries long-term mental toll, study finds
Adolescent and young adult cancer survivors exhibit persistently elevated levels of depression and anxiety throughout their lifespan, but only symptoms of anxiety tend to stabilize in their later years, say University of Michigan researchers.
Allowing small portions of desired foods in meals linked to lower cravings and greater weight loss
Food cravings are the downfall of many dieters, who feel locked in an eternal battle with their willpower to resist the tempting sweets, snacks and other foods they love.
Virtual trial shows combo rescue inhaler nearly halves severe asthma attacks
Findings from a first-of-its-kind virtual trial in pulmonary medicine, conducted at Rutgers and many other institutions, suggest adding an inhaled corticosteroid to rescue therapy could sharply reduce the danger of severe attacks for millions of people with mild asthma.