Cutting HIV aid means undercutting US foreign and economic interests. Nigeria shows the human costs

A little over two decades ago, addressing Nigeria’s HIV crisis topped U.S. President George W. Bush’s priorities. Africa’s most populous nation had 3.5 million HIV cases, and the disease threatened to destabilize the region and ultimately compromise U.S. interests. These interests included securing access to Nigeria’s substantial oil reserves, maintaining regional military stability and protecting trade partnerships worth billions.

Brain inflammation linked to repetitive behaviors in autism and obsessive-compulsive disorder

A research team has unveiled the cause and molecular mechanism of chronic brain inflammation that results in repetitive behavioral disorders. The research team demonstrated that an inflammatory response by immune cells in the brain induces overactivity in certain receptors, which may, in turn, lead to the meaningless repetitive behaviors observed in people with autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD).

Proteins regulating NMDA receptor function offer hope for targeted autism therapies

A research team has identified a molecular mechanism that coordinates the operation of the N-methyl-D-aspartate (NMDA) glutamate receptor, which is key to regulating excitatory synapse function in the brain. This achievement paves the way for the precise control of excitatory synapse function in specific neural circuits and may provide important clues for developing treatments for brain diseases such as autism spectrum disorders.