Researchers have discovered how an ion channel in the brain’s neurons has a kind of “molecular memory,” which contributes to the formation and preservation of lifelong memories. The researchers have identified a specific part of the ion channel at which new drugs for certain genetic diseases could be targeted. The study, led by Linköping University in Sweden, has been published in Nature Communications.
New at-home cervical cancer tests are a good alternative, but won’t completely replace Pap smears, experts say
Many women dread getting their regular Pap smears. The procedure, which involves scraping cells from the cervix to check for HPV and cancer, is often uncomfortable for patients.
A clearer look at diabetic kidney disease via new optical imaging technology
Scientists from the University of California San Diego and Washington University School of Medicine in St. Louis have developed a powerful new way to look inside kidney tissues—without needing to stain or damage the tissue samples. The new technique, called label-free multimodal optical biopsy, captures detailed, 3D images of kidney samples and reveals early signs of disease often missed by traditional methods.
Obesity drugs found to improve emotional well-being as well as physical health
A major new meta-analysis from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London has found that glucagon-like peptide 1 receptor agonists (GLP1-RAs)—a class of medications used to treat obesity and diabetes—may also offer benefits for emotional well-being in overweight users.
Amiloride found to be as effective as spironolactone in managing resistant hypertension
Yonsei University College of Medicine-led research has shown amiloride is as effective as spironolactone in reducing systolic blood pressure (SBP) over 12 weeks in patients with resistant hypertension.
Why donor hearts fail in cold storage—and how to prevent it
Researchers have discovered a new molecular process that occurs when donor hearts are preserved in cold storage which contributes to failure after transplant, a study in both humans and animals shows.
Wearable technologies power study on differences between treadmill, outdoor running on injury risk
When researchers study runners, up until very recently, they have had to conduct these studies in the lab using a treadmill.
AI chatbots miss key signs of psychiatric drug reactions, lag behind expert advice
Asking artificial intelligence for advice can be tempting. Powered by large language models (LLMs), AI chatbots are available 24/7, are often free to use, and draw on troves of data to answer questions. Now, people with mental health conditions are asking AI for advice when experiencing potential side effects of psychiatric medicines—a decidedly higher-risk situation than asking it to summarize a report.
Scientists call into question safety of potential new anticancer treatment
Scientists have discovered that a promising new anticancer medicine currently in development could be made from unknown dangerous compounds. This discovery could overturn over 60 years of chemistry and almost 100 publications.
Study finds mix of incentives, texts, and local outreach boosts immunization rates
Around the world, low immunization rates for children are a persistent problem. Now, an experiment conducted in India shows that an inexpensive combination of methods, including text reminders and small financial incentives, has a major impact on immunization.