Estimating complex immune cell structures by AI tools for survival prediction in advanced melanoma

Researchers from the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) have applied AI-driven processes for detecting tertiary lymphoid structures (TLS) in thousands of digital images of melanoma tumor tissue, significantly enhancing TLS identification and survival predictions for operable stage III/IV patients. The presence of TLS, a key biomarker for better prognosis and improved survival, is not yet a standard part of patients’ pathology reports, and manual detection is labor-intensive and can be variable.

Belgium’s euthanasia trends dispute ‘slippery slope’ argument: New study

Euthanasia has been legal in Belgium since mid-2002, and in the past two decades, the number of reported cases has risen sharply. In 2003, only 236 cases were recorded, but by 2023, this had increased to 3,423. This means that euthanasia now accounts for around 3% of all deaths. But what explains this increase? And does it suggest a worrying trend, as some critics fear?

Dementia care: Are terms of endearment like ‘sweetheart’ comforting or condescending?

In the emotionally complex world of dementia care, communication is more than just what we say—it’s how we say it. Terms of endearment like “darling,” “my lovely,” and “sweetheart” are often used by health care staff with the best intentions: to comfort, connect, and show warmth. But some people believe that elderspeak may sound patronizing.

Study finds recent Haitian immigrants at increased risk for adverse pregnancy, post-partum outcomes

Pregnancy and postpartum are critical time periods when immigrants may be particularly vulnerable to unmet medical and social needs. A 2023 report from the Massachusetts Department of Public Health revealed that foreign-born Massachusetts residents are 1.4 times more likely to experience severe maternal morbidity compared with US-born residents.

New tumor therapy approach reduces costs and side effects while increasing accessibility

Radiation therapy is an established method of cancer treatment. It works by subjecting tumor cells to ionizing radiation, damaging their genetic material and, ideally, eliminating the tumor. Researchers have long been working on methods for directing as much radiation as possible at tumors while avoiding harm to surrounding tissue, but thus far it has proven impossible to prevent damage to the skin and healthy organs when treating internal tumors.