Patients with generalized pustular psoriasis (GPP) experience frequent flares, and treatment alterations of off-label agents are frequently observed, according to a study recently published online in the Journal of the American Academy of Dermatology.
Q&A: Why SNAP food restrictions don’t improve health outcomes, while incentive programs show promise
In a move sparking debate across the nutrition policy landscape, several states are exploring restrictions on how Supplemental Nutrition Assistance Program (SNAP) benefits can be used. U.S. Health and Human Services Secretary Robert F. Kennedy Jr. has recently encouraged states to consider the move, while states including Texas, Montana, and Idaho are pushing to extend restrictions to items like chips and candy.
Pushing the limits of brain imaging: A new tool for targeted delivery of imaging agents and drugs
Multiphoton microscopy is a valuable tool for neuroscience research, allowing scientists to observe functional brain activity in real time through high-resolution imaging. An essential component of many multiphoton microscopy imaging studies is the delivery of chemical compounds, including imaging agents and drugs. However, many compounds cannot cross the blood-brain barrier and, therefore, cannot be delivered to the brain through systemic administration.
Discovery of FOXR2 activation in various brain tumors refines diagnosis to improve care
Physicians classify brain tumors and determine treatment options, in part, by the genes they express. According to World Health Organization standards, the abnormal activation of oncogene FOXR2 only occurs in central nervous system (CNS) neuroblastoma, but that may not be true. Findings from St. Jude Children’s Research Hospital show FOXR2 activation in multiple pediatric CNS tumor types, mostly brain tumors, with significantly different clinical outcomes.
Researchers explore adapted Argentine dance therapy for cancer survivors
Adapted Argentine tango dance therapy is helping some breast cancer survivors regain natural balance and sensation after experiencing neuropathy, a common side effect of chemotherapy treatment. Expansion of a new clinical study will look further at how this musical movement intervention can “rewire” the brain to improve function after chemotherapy-related nerve changes.
Even vegans who get enough total protein may fall short for some essential amino acids, findings suggest
In a new study of people with long-term vegan diets, most ate an adequate amount of total daily protein, but a significant proportion did not meet required levels of the amino acids lysine and leucine. Bi Xue Patricia Soh and colleagues at Massey University, New Zealand, present these findings in the open-access journal PLOS One.
Lifelong physical activity may slow cognitive decline
High levels of physical activity may mitigate brain loss in adults and help maintain long-term cognitive health, researchers at UT Southwestern Medical Center report in a study published in the Journal of Applied Physiology.
Genomic analysis provides insight into underpinnings of new treatment combination for deadly, Asian-prevalent lymphoma
A multinational research team of clinicians and scientists from South Korea and Singapore has published positive findings from a phase 2 clinical trial for a new combination therapy for an aggressive, Asian-prevalent blood cancer, extranodal NK/T-cell lymphoma.
Reprogramming cancer cells to treat an aggressive type of leukemia
A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains just 8.5 months.
New human ‘multi-zonal’ liver organoids improve injury survival in rodents
One reason why our livers excel at clearing waste from our blood system is that the organ functions according to three key “zones” that perform specific major tasks. So, if scientists hope to create self-growing patches of liver organoid tissue that could help repair damaged organs, it’s important that the lab-grown tissue faithfully reproduce such zones.