A Cleveland Clinic-led clinical trial of tolebrutinib, an investigational oral Bruton’s tyrosine kinase inhibitor, a group of drugs originally developed to treat lymphomas and related blood disorders, demonstrated a 31% delay in the onset of six-month confirmed disability progression (CDP) in patients with non-relapsing secondary progressive multiple sclerosis (SPMS).
New research from Weill Cornell Medicine has uncovered a surprising culprit underlying cardiovascular diseases in obesity and diabetes—not the presence of certain fats, but their suppression. The study, published Feb. 25 in Nature Communications, challenges the conventional belief that a type of fat called ceramides accumulates in blood vessels to cause inflammation and health risks.
BARNABAS ZULU INCUMBENT National Olympics Committee of Zambia (NOCZ) President Alfred Foloko who was reelected unopposed has promised to put in place a new strategic direction that will shift the focus of the association. Speaking after being reelected, Foloko reaffirmed his dedication to advancing the goals set out in the NOCZ Strategic Plan 2022–2028. He […]
Agricultural employers who provide farmworkers with health insurance earn higher profits, even after accounting for the cost of that coverage. In addition, farmworkers who get health insurance through their employers are more productive and earn more money than those who do not.
The world’s largest and most comprehensive study of the long-term health impacts of flooding—via analysis of over 300 million hospitalization records in eight countries prone to flooding events—has found an increased risk of 26% of all diseases serious enough to require hospitalization. This impact on the health of communities lasts up to seven months post event.
Experimental drug NU-9—a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS)—improves neuron health in animal models of Alzheimer’s disease, according to a new Northwestern University study.
Researchers have developed a handheld device that could potentially replace stethoscopes as a tool for detecting certain types of heart disease.
As scientists seek to unravel the intricate potential connections between nutrition and the aging brain, a new study from researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University is shedding light on how insufficient consumption of vitamin K may adversely affect cognition as people get older.
Organoids are made to model human organs and are promising for research and therapy, but there are limitations to their growth and function. A recent study by researchers at The University of Tokyo found that placenta-derived IL1α, under hypoxic conditions, can greatly increase the growth of human stem cell-derived liver organoids. By promoting liver progenitor cell expansion through a specific signaling pathway, this method offers a promising route to improve organoid models and regenerative medicine.
Researchers have shown that differences in the entire rotavirus genome—not just its two surface proteins—affect how well vaccines work, helping to explain why some strains are more likely to infect vaccinated individuals.