Although a plethora of medications and therapies now exist for major depression, roughly one in three diagnosed patients still suffer from treatment-resistant depression (TRD)—a form of the disorder that does not respond to first-line antidepressants. Even when traditional drugs work, they often take weeks to kick in, delaying relief for people in crisis.
World-first guidelines developed for complicated UTIs in children
A new guideline on complicated urinary tract infections (UTIs) could redefine treatment in Australia and globally.
Do vowels have colors? According to some with synesthesia, yes.
It’s hard to pinpoint when synesthesia, the rare neurological condition where a stimulus that affects one sense prompts a response in a different sense, was first documented. Scientific literature marks its beginning in 1812, when it appeared as an aside in a Bavarian medical student’s dissertation. Toward the end, there’s a small section where he detailed how he associated musical tones and letters with colors.
AI-powered database spotlights medication risks to improve drug safety
A multicenter study led by Cedars-Sinai created a database of adverse medication events—the fourth leading cause of death in the United States and a medical issue costing more than $500 billion annually.
People are getting costly stem cell injections for knee osteoarthritis, but we don’t know if they work
More than 500 million people around the world live with osteoarthritis. The knee is affected more often than any other joint, with symptoms (such as pain, stiffness and reduced movement) affecting work, sleep, sport and daily activities.
Gut microbiome therapy may delay onset of type 1 diabetes, study finds
Researchers at the University of Queensland have found that improving the function of the gut microbiome may delay the onset of type 1 diabetes (T1D). The study was published in Nature Communications.
A failed fragile X syndrome drug can reduce cocaine use, clinical trial finds
A team of pharmaceutical researchers at Novartis Biomedical Research, working with an international team of associates, has found that the drug mavoglurant can reduce use in people with cocaine use disorder. In their study, published in the journal Science Translational Medicine, the group conducted a Phase II clinical trial with 68 people with a diagnosed cocaine use disorder.
Why do women get ‘reassurance scans’ during pregnancy? And how can you spot a suspicious provider?
Recent media coverage in the Nine newspapers highlights a surge in non-medical ultrasound providers offering “reassurance ultrasounds” to expectant parents.
New global guidelines to treat schizophrenia
New guidelines have been developed for the treatment of schizophrenia through a collaborative effort of international experts from 30 countries. The recommendations are published in The Lancet Psychiatry journal.
With measles on the rise, nurse practitioners can help address vaccine hesitancy, expert says
Listening, building trust and providing evidence-based resources are just some of the ways that nurse practitioners, or NPs, can play an impactful role in addressing vaccine hesitancy and combating misinformation.